Inhibition of Photosynthetic Electron Transport by the Quinone Antagonist UHDBT

Walter Oettmeier 1 , Klaus Masson 1  and Doris Godde 1
  • 1 Lehrstuhl Biochemie der Pflanzen, Ruhr-Universität, Postfach 10 21 48, D-4630 Bochum 1, Bundesrepublik Deutschland

UHDBT (5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole) is an efficient inhibitor of photosynthetic electron transport in chloroplasts from spinach (pI50-value = 7.61) and the green alga Chlamydomonas reinhardii. At low concentrations of UHDBT its site of inhibition is located at the reducing side of plastoquinone, identical to that of 3-(3,4-dichlorophenyl)-1, 1-dimethylurea (DCMU). This became evident from functional as well as binding studies. At higher concentrations of UHDBT a secondary inhibition site at the oxidizing side of plastoquinone, identical to that of 2,5-dibromo-3-methyl-6-isopropyl-1,4-benzoquinone (DBMIB) becomes evident

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A Journal of Biosciences: Zeitschrift für Naturforschung C (ZNC) is an international scientific journal for the emerging field of natural and natural-like products. ZNC publishes original research on the isolation, bio-chemical synthesis and bioactivities of natural products, their biochemistry, pharmacology, biotechnology, and biological activity and innovative developed computational methods for predicting their structure and/or function.