Flavonoids and Terpenoids from the Resinous Exudates of Madia Species (Asteraceae, Helenieae)

Eckhard Wollenweber 1 , Marion Dörr 1 , Marco Dörsam 1 , Abu El-Hamed Hassan 2 , 3 , Ahmed A. Ahmed 4 , M. F. Hegazy 4  and Klaus-Peter Zeller 3
  • 1 Institut für Botanik der Technischen Universität, Schnittspahnstrasse 3, D-64287 Darmstadt, Germany
  • 2 Department of Chemistry, Aswan-Faculty of Science, South Valley University, Aswan, Egypt
  • 3 Institut für Organische Chemie, Universität Tübingen, D-72076 Tübingen, Germany
  • 4 Department of Chemistry, Faculty of Science, El-Minia University, El-Minia 61519, Egypt

The resinous material accumulated on aerial parts of Madia species is shown to consist mainly of diterpenes, containing a series of flavonoid aglycones. A6- and/or 8-O-substitution is characteristic for many of these flavonoids. Three known rare diterpenes were found and the structure elucidation of a diterpene with a new carbon skeleton, named madiaol, is reported.

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A Journal of Biosciences: Zeitschrift für Naturforschung C (ZNC) is an international scientific journal for the emerging field of natural and natural-like products. ZNC publishes original research on the isolation, bio-chemical synthesis and bioactivities of natural products, their biochemistry, pharmacology, biotechnology, and biological activity and innovative developed computational methods for predicting their structure and/or function.